Early game · first 8 minutes
Stay close enough for your lane partner to help. If Scrap Grenade hits Drifter, shoot from beside your lane partner instead of chasing him alone.
Rat King vs Drifter
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Mid game · Walkers
Keep Royal Pestments for his ambush. When he attacks, send rats and focus fire with the teammate he targeted.
Late game · Patron
Eternal Night counts you as isolated even beside teammates. Use Royal Pestments when Drifter reaches you, and stay close enough for your team to shoot him.