Early game · first 8 minutes
Keep a dash for Leaping Slash. If she misses, send rats and shoot while backing out of melee range.
Rat King vs Calico
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Mid game · Walkers
Keep Royal Pestments ready for her first burst. Don’t follow her around a blind corner where she or a teammate can attack before you see them.
Late game · Patron
Wait for Calico to reappear from Return to Shadows before slamming your banner down. Move away during her shadow form to avoid the returning blast.